Yesterday Microsoft (finally?) released UR#2 for SCOM 2016. KB3209591 tells all about it, what fixes it contains. Some of those fixes address issues which are for quite some time already in SCOM, even back to 2007x, like Groups disappearing when added to a Distributed Application.
UR#2 for SCOM 2016 touches ALL SCOM 2016 components, as you can see in the Microsoft Update Catalog.
UR#2 is applied in the same manner as the ones before. I expect Kevin Holman to post an article about it soon .